Department ofPhysics of Complex Systems

Neuronal logic & devices

Prof. Elisha Moses

01 / Research

Research

The group studies neuronal networks as physical systems, using cultures of dissociated neurons grown on multi-electrode arrays and patterned substrates to ask how computation and collective dynamics emerge from many coupled excitable cells. By shaping connectivity, stimulating subpopulations, and reading out spiking activity, the lab probes how a culture integrates inputs, propagates activity bursts, and can be coaxed into performing elementary logical operations—effectively asking what it takes to build a device from living neural tissue.

A second thread develops physical tools to stimulate and observe neural activity, combining magnetic stimulation with optical and electrical measurement of the response. Because magnetic fields penetrate tissue with minimal attenuation, understanding how induced currents excite neurons connects directly to the physics of transcranial magnetic stimulation and to noninvasive readout of brain dynamics. Together these lines treat the nervous system as a substrate whose excitability, geometry, and noise set the rules for both natural function and engineered behavior.

Multi-electrode arraysPatterned neuronal culturesMagnetic stimulationCalcium and voltage imagingSpike-train analysisNetwork modeling
Logic from neuronal culturesEngineering patterned cultures whose evoked activity implements thresholding and elementary logical operations as a step toward biological computing devices.
Magnetic stimulation of neuronsQuantifying how induced electric fields excite neurons to ground transcranial magnetic stimulation in cellular biophysics.
Optical readout of activityUsing calcium and voltage imaging to map network-wide responses to controlled stimulation in real time.
Bursts and network dynamicsCharacterizing the spontaneous synchronization, propagation fronts, and excitability that govern collective activity in cultured networks.
Connectivity and geometryShaping substrate topology to test how wiring constraints determine signal flow and computational capacity.
02 / People

Group members

Special contracts 2
  • Dr. Dominik Freche
  • Dr. Eyal Weinreb
MSc students 1
  • Taylor Lauren Froomin
Research support 2
  • Dr. Yuri Burnishev
  • Dr. Nadav Matalon
Listed on the group page, position not in the directory 1
  • Eden Ozeri

6 people are listed with this group, besides the principal investigator. Names and categories are as published in the Weizmann directory and on the group's own page; rooms, phone numbers and e-mail addresses are on the People page.

03 / Output

Recent publications

All publications